Biohybrid Artificial Lung

• Composed of microfabricated units that mimic exchange sacs of natural lungs
• Vascular cells coat blood pathways for improved blood biocompatibility
• Compact respiratory device design compared to traditional respiratory devices

Questions about this project, please contact Kristie Burgess
at henchirk@upmc.edu

Specific Antibody Filter (SAF)

• Extracorporeal fiber module that selectively removes pathogenic antibodies
• Antigenic ligands coat fiber lumens to bind antibodies with specificity
• Removes antibodies causing certain forms of transplanted organ rejection

Questions about this project, please contact Shalini Gautam
at gautams@upmc.edu

Polymer, Fiber and Surface Modifications

• Fiber polymer coatings for improved blood biocompatibility
• Attachment of biomolecules on fibers to provide novel functionality
• Coatings of active polymeric microspheres on membrane surfaces

Questions about this project, please contact Heung Oh
at ohh@upmc.edu

Systems Engineering of a Pheresis Intervention for Sepsis (SEPsIS) Hemoadsorption Device

• Extracorporeal blood purification device that removes the inflammatory molecules which cause severe sepsis
• Device packed with adsorbing polymer beads covered in biocompatible coating
• Cytokines involved in sepsis adsorbed on beads

Questions about this project, please contact Morgan DiLeo at dileomv@upmc.edu