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Kumar, R.; Clermont, G.; Vodovotz, Y.; Chow, C. C. The dynamics of acute inflammation. J.Theoretical Biol. 2004. 230:145-155 Clermont, G.; Bartels, J.; Kumar, R.; Constantine, G.; Vodovotz, Y.; Chow, C. In silico design of clinical trials: a method coming of age. Crit Care Med. 2004. 32:2061-2070
Chow, C. C.; Clermont, G.; Kumar, R.; Lagoa, C.; Tawadrous, Z.; Gallo, D.; Betten, B.; Bartels, J.; Constantine, G.; Fink, M. P.; Billiar, T. R.; Vodovotz, Y. The acute inflammatory response in diverse shock states. Shock 2005. 24:74-84 Reynolds, A.; Rubin, J.; Clermont, G.; Day, J.; Vodovotz, Y.; Ermentrout, G. B.. A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. J.Theor.Biol. 2006. 242:220-236 Day, J.; Rubin, J.; Vodovotz, Y.; Chow, C. C.; Reynolds, A.; Clermont, G.. A reduced mathematical model of the acute inflammatory response: II. Capturing scenarios of repeated endotoxin administration. J.Theor.Biol. 2006. 242:237-256 Prince, J.M.; Levy,R.M.; Bartels, J.; Baratt, A.; Kane, J.M. III; Lagoa, C.; Rubin, J.; Day, J.; Wei, J.; Fink, M.P.; Goyert, S.; Clermont, G.; Billiar, T.R.; Vodovotz, Y. In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice. Mol. Med., 2006. 12:88-96 Lagoa, C.E.; Bartels, J.; Baratt, A.; Tseng, G.; Clermont, G.; Fink, M.P.; Billiar, T.R.; Vodovotz, Y. The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis. Shock, 2006. 26:592-600 Mi, Q.; Rivière, B.; Clermont, G.; Steed, D.L. ; Vodovotz, Y. Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-?1. Wound Repair Reg. 2007. 15:671-682 Mi, Q.; Rivière, B.; Cetin, S.; Swigon, D. ; Vodovotz, Y. ; Hackam, D. One-dimensional elastic continuum model of epithelial wound healing. Biophys. J. 2007. 93:3745-3752 Kumar, R.; Chow, C.C.; Bartels, J.; Clermont, G.; Vodovotz, Y. A mathematical simulation of the inflammatory response to anthrax infection. Shock. 2008. 29:104-111 Li, N.Y.K.; Verdolini, K.; Clermont, G.; Mi, Q.; Hebda, P.A.; Vodovotz, Y. A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury. PLoS ONE. 2008. 3:e2789. Daun, S.; Rubin, J.; Vodovotz, Y.; Roy, A.; Parker, R.; Clermont, G. An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: Results from parameter reduction. J. Theoretical Biol. 2008. 253:843-853 Rivière, B.; Epshteyn, Y.; Swigon, D.; Vodovotz, Y. A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior. Math. Biosci. 2009. 217:19-26 Torres, A.; Bentley, T.; Bartels, J.; Namas, R.; Zamora, R.; Puyana, J.C.; Vodovotz, Y. Mathematical modeling of post-hemorrhage inflammation in mice: Studies using a novel, computer-controlled, closed-loop hemorrhage apparatus. Shock. 2009. 32:172-178 Li, N.Y.K.; Vodovotz, Y.; Hebda, P. Verdolini, K. Biosimulation of inflammation and healing in surgically injured vocal folds. Ann. Otology Rhinol. Laryngol. 2010. 119:412-423 Brown, B.; Price, I.; Toapanta, F.R.; DeAlmeida, D.R.; Wiley, C.A.; Ross, T.M.; Oury, T.D.; Vodovotz, Y. An Agent-based model of inflammation and fibrosis following particulate exposure in the lung. Math. Biosci. 2011. 231:186-196 Mi, Q.; Constantine, G.; Ziraldo, C.; Solovyev, A.; Torres, A.; Namas, R.; Bentley, T.; Billiar, T.R.; Zamora, R.; Puyana, J.C.; Vodovotz, Y. A dynamic view of trauma/hemorrhage-induced inflammation in mice: Principal drivers and networks. PLoS ONE. 2011.6:19424 Li, N.Y.K.; Vodovotz, Y.; Kim, K.H.; Mi, Q.; Hebda, P.A.; Verdolini Abbott, K. Biosimulation of acute phonotrauma: An extended model. Laryngoscope 2011. 121:2418-2428 Nieman, G.; Brown, D.; Sarkar, J.; Kubiak, B.; Ziraldo, C.; Dutta-Moscato, J.; Vieau, C.; Barclay, D.; Gatto, L.; Maier, K.; Constantine, G.; Billiar, T.R.; Zamora, R.; Mi, Q.; Chang, S.; Vodovotz, Y. A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine: Insights from combined data-driven and mechanistic modeling. Crit. Care Med. 2012. Apr;40(4):1052-1063 |
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